Surgically correctable forms of primary aldosteronism are generally held to be less common than forms requiring medical therapy. However, with the availability of improved diagnostic techniques and the adoption of a systematic and thorough diagnostic work-up they can be identified more commonly than expected. Adrenal vein sampling (AVS) for measurement of cortisol and aldosterone has emerged as the 'gold standard' diagnostic test for identifying unilateral causes of primary aldosteronism that are amenable to surgical cure. Adrenalectomy can provide long-term normalisation of blood pressure and correction of primary aldosteronism in about 55% of patients with an aldosterone-producing adenoma and can markedly ameliorate blood pressure control in the rest. This chapter summarises the diagnostic work-up suggested for identifying these forms and examines the other diseases mimicking mineralocorticoid excess that enter into the differential diagnosis of surgically curable primary aldosteronism.

译文

手术可纠正的原发性醛固酮增多症的形式通常被认为比需要药物治疗的形式不常见。但是,随着改进的诊断技术的可用性以及系统而彻底的诊断工作的采用,可以比预期的更普遍地识别它们。用于测量皮质醇和醛固酮的肾上腺静脉采样 (AVS) 已成为 “金标准” 诊断测试,用于确定可手术治愈的原发性醛固酮增多症的单侧原因。肾上腺切除术可提供约55% 的产生醛固酮的腺瘤患者的血压长期正常化和原发性醛固酮增多症的纠正,并可显着改善其余患者的血压控制。本章总结了建议用于识别这些形式的诊断工作,并检查了其他模仿盐皮质激素过量的疾病,这些疾病进入了手术可治愈的原发性醛固酮增多症的鉴别诊断疾病。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录