Submitochondrial particles prepared from rat liver during hepatic regeneration exhibit a depressed ATPase activity which is correlated with a decrease in F1 subunit content as shown by SDS-PAGE. Use of an antibody directed against the F1 portion of the H+-ATPase complex demonstrated that there is a definite decrease in the amount of beta-subunit of F1 in both submitochondrial particles and mitochondria from rat liver 24 h after partial hepatectomy.

译文

在肝再生过程中从大鼠肝脏制备的亚线粒体颗粒表现出降低的ATPase活性,这与F1亚基含量的降低有关,如sdds-PAGE所示。使用针对H-ATPase复合物的F1部分的抗体表明,部分肝切除术后24小时,大鼠肝脏的线粒体颗粒和线粒体中F1的 β 亚基数量均明显减少。

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