We review a 15-year experience with childhood idiopathic thrombocytopenic purpura (ITP) at a tertiary-care pediatric hospital in Croatia. Data confirm that ITP is typically a self-limited bleeding disorder that usually presents with mild symptoms in children between 1 and 10 years of age and affects both sexes equally. At presentation, more than half of the children had platelet counts of <10x10(9)/L. The absence of preceding viral infection and insidious onset of symptoms were significantly associated with development of chronic ITP. In our experience, observation without specific therapy seems to be the optimal approach to a child with ITP.

译文

我们回顾了克罗地亚一家三级儿科医院对儿童特发性血小板减少性紫癜 (ITP) 的15年经验。数据证实,ITP通常是一种自限性出血性疾病,通常在1至10岁的儿童中表现为轻度症状,并且对男女影响均等。在演讲中,超过一半的儿童的血小板计数 <10x10(9)/L。先前没有病毒感染和症状的隐匿性发作与慢性ITP的发展显着相关。根据我们的经验,没有特定疗法的观察似乎是治疗ITP儿童的最佳方法。

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