In this retrospective cohort study, we describe acceptability, tolerability and potential efficacy of cognitive behavioural therapy (CBT) in Insomnia Disorder subtypes, derived from polysomnography (PSG): insomnia with normal-sleep duration (I-NSD) and insomnia with short-sleep duration (I-SSD). All research volunteers were offered access to digital CBT, single component sleep restriction therapy and face-to-face group CBT. Follow-up occurred at three months post-treatment using the insomnia severity index (ISI). 96 participants (61 females, mean age of 41 years) were grouped into either normal-sleep (n = 53) or short-sleep (n = 43). CBT was acceptable to 63% of participants (normal-sleep = 31, short-sleep = 29), with 28 completing therapy (tolerability: normal-sleep = 11, short-sleep = 17). For potential efficacy, 39 (normal-sleep = 20, short-sleep = 19) out of 96 participants (41%) completed a follow-up ISI assessment. In this reduced sample, mean (SD) ISI scores decreased across both groups (normal-sleep: 18.0 (4.0) to 10.7 (4.6); short-sleep: 16.5 (5.5) to 11.0 (6.3); both P < 0.01). Those with normal-sleep were more likely to respond (≥6-point ISI reduction) to CBT compared to short-sleep (70%, n = 14/20 vs. 37%, n = 7/19 respectively, P = 0.038). In this cohort, 60 (63%) of participants attempted CBT and of those 28 (47%) completed therapy. Results may be comparable to clinical participants with implications for the successful translation of CBT for insomnia.

译文

在这项回顾性队列研究中,我们描述了认知行为疗法 (CBT) 在失眠疾病亚型中的可接受性,耐受性和潜在功效,这些疾病源自多导睡眠图 (PSG): 睡眠时间正常的失眠 (I-NSD) 和睡眠时间短的失眠 (I-SSD)。所有研究志愿者都可以使用数字CBT,单成分睡眠限制疗法和面对面组CBT。使用失眠严重程度指数 (ISI) 在治疗后三个月进行随访。96名参与者 (61名女性,平均年龄41岁) 被分为正常睡眠 (n   =   53) 或短睡眠 (n   =   43)。CBT可接受63% 的参与者 (正常睡眠   =   31,短睡眠   =   29),28例完成治疗 (耐受性: 正常睡眠   =   11,短睡眠   =   17)。对于潜在疗效,96名参与者 (41% 名) 中有39名 (正常睡眠   =   20,短睡眠   =   19) 完成了ISI随访评估。在这一减少的样本中,两组的平均 (SD) ISI得分均降低 (正常睡眠: 18.0 (4.0) 至10.7 (4.6); 短睡眠: 16.5 (5.5) 至11.0 (6.3); 两者p <  0.01)。与短睡眠 (70%,n   =   14/20 vs. 37%,n   =   7/19,p   =   0.038) 相比,睡眠正常的人更容易对CBT产生反应 (ISI降低 ≥ 6点)。在该队列中,60 (63%) 参与者尝试了CBT,其中28 (47%) 完成了治疗。结果可能与临床参与者相当,对成功翻译CBT治疗失眠有影响。

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