Constipation is a common and chronic problem in children worldwide. Long-term use of laxatives is necessary for successful treatment of chronic constipation. Commonly used laxatives in children include milk of magnesia, lactulose, mineral oil, and polyethylene glycol (PEG). Recent studies report the efficacy and safety of PEG for the long-term treatment of constipation in children. Because of its excellent patient acceptance, PEG is being used widely in children for constipation. In this commentary, we review the recently published pediatric literature on the efficacy, safety, and patient acceptance of PEG. We also assess the role of PEG in childhood constipation by comparing it with other laxatives in terms of efficacy, safety, patient acceptance, and cost.

译文

便秘是全世界儿童的常见和慢性问题。长期使用泻药对于成功治疗慢性便秘是必要的。儿童常用的泻药包括氧化镁,乳果糖,矿物油和聚乙二醇 (PEG) 的牛奶。最近的研究报告了PEG长期治疗儿童便秘的疗效和安全性。由于其出色的患者接受度,PEG已广泛用于儿童便秘。在这篇评论中,我们回顾了最近发表的有关PEG的疗效,安全性和患者接受度的儿科文献。我们还通过将PEG与其他泻药在功效,安全性,患者接受度和成本方面进行比较,评估了PEG在儿童便秘中的作用。

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