The antigenicity of the major outer membrane protein of Chlamydia trachomatis serovar C was assessed by using overlapping hexapeptide homologs of serovar C major outer membrane protein and rabbit antisera in a peptide enzyme-linked immunosorbent assay. Five immunogenic sites were found distributed within variable sequences of the protein: four were immunodominant and three were surface exposed on native elementary bodies of serovar C. None was surface exposed on serovars H, I, and J.

译文

通过在肽酶联免疫吸附试验中使用血清C主要外膜蛋白和兔抗血清的重叠六肽同源物评估沙眼衣原体血清型C主要外膜蛋白的抗原性。在蛋白质的可变序列中发现了五个免疫原性位点: 四个是免疫优势,三个表面暴露在血清型C的天然基本体上。没有一个表面暴露在血清型H,I和J上。

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