This prospective study validates the finding from retrospective research that having an inpatient lay care-partner (CP) is associated with better survival following allogeneic BMT. Compared with patients without a CP (n=76), patients with a CP (n=88) have significantly better OS (P=0.017) and relapse-free survival (RFS) (P=0.020). Four-year and median survivals were 42% and 36 months among patients with CPs, compared with 26% and 10 months among those without CPs. Four-year survival and median RFS were 39% and 25 months among those with CPs, compared with 23% and 7 months among those without CPs. Further, better survival and RFS were associated with CP visit duration of >3 h per day (P=0.005 and P=0.007, respectively) and with CP frequency of visits >75% of inpatient days (P=0.004 and P=0.010, respectively). A CP support program should encourage not only presence of a CP but also duration and frequency of CP visits associated with better patient survival.

译文

这项前瞻性研究证实了回顾性研究的发现,即拥有住院非专业护理伴侣 (CP) 与同种异体BMT后更好的生存率相关。与没有CP的患者 (n = 76) 相比,具有CP的患者 (n = 88) 具有明显更好的OS (P = 0.017) 和无复发生存率 (RFS) (P = 0.020)。CPs患者的4年和中位生存期分别为42% 和36个月,而无CPs的患者为26% 和10个月。患有CPs的患者的四年生存率和中位RFS分别为39% 和25个月,而没有CPs的患者为23% 和7个月。此外,更好的生存率和RFS与每天> 3 h的CP访视时间 (分别为P = 0.005和P = 0.007) 和CP访视频率> 住院天数的75% (分别为P = 0.004和P = 0.010) 相关。CP支持计划不仅应鼓励CP的存在,而且还应鼓励CP就诊的持续时间和频率与更好的患者生存率相关。

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