As an essential lipid, cholesterol is of great value in keeping cell homeostasis, being the precursor of bile acid and steroid hormones, and stabilizing membrane lipid rafts. As a kind of cholesterol metabolite produced by enzymatic or radical process, oxysterols have drawn much attention in the last decades. Among which, the role of 25-hydroxycholesterol (25-HC) in cholesterol and bile acid metabolism, antivirus process, and inflammatory response has been largely disclosed. This review is aimed at revealing these functions and underlying mechanisms of 25-HC.

译文

作为一种必需的脂质,胆固醇在保持细胞稳态,胆汁酸和类固醇激素的前体以及稳定膜脂筏方面具有重要价值。作为一种通过酶促或自由基过程产生的胆固醇代谢产物,氧化甾醇在过去的几十年中引起了广泛的关注。其中,25-羟基胆固醇 (25-HC) 在胆固醇和胆汁酸代谢,抗病毒过程和炎症反应中的作用已被广泛公开。这篇综述旨在揭示25-hc的这些功能和潜在机制。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录