BACKGROUND:Infantile hemangioma (IH) can lead to severe complications. The 595-nm pulsed dye laser is poorly effective on thick and deep IH. Long-pulsed alexandrite laser has the proper wavelength of 755 nm and a relatively deep penetration. Thus, this may be a safe and effective treatment method for relatively deep or thick IH. AIMS AND OBJECTIVES:This study aims to determine whether 595-nm pulsed dye laser and 755-nm long-pulsed alexandrite laser in sequential therapy are safer and more effective for relatively deep or thick hemangioma. MATERIALS AND METHODS:This was a prospective study. A total of 194 infantile IH patients (thickness greater than 2 mm and less than 8 mm) were randomly divided into two groups: control group (treated using 595-nm pulsed dye laser) and experimental group (treated by sequential therapy with 755-nm long-pulsed alexandrite laser and 595-nm dye laser). RESULTS:The control group had a total effective rate of 36.1%, while the experimental group had a total effective rate of 76.3%. Enumeration data were compared by X2 -test. The results were considered statistically significant at P < .05. CONCLUSION:Sequential therapy with 755-nm pulsed dye laser and 595-nm long-pulsed alexandrite laser is a safe and effective treatment approach for relatively deep or thick hemangioma.

译文

背景:小儿血管瘤(IH)可导致严重的并发症。 595 nm脉冲染料激光对厚和深IH效果不佳。长脉冲变石激光器具有适当的755 nm波长和相对较深的穿透力。因此,对于相对较深或较厚的IH,这可能是一种安全有效的治疗方法。
目的和目的:本研究旨在确定序贯治疗中的595 nm脉冲染料激光和755 nm长脉冲变石激光对于相对较深或较厚的血管瘤是否更安全,更有效。
材料与方法:这是一项前瞻性研究。总共194名婴儿IH患者(厚度大于2 mm且小于8 mm)被随机分为两组:对照组(使用595 nm脉冲染料激光治疗)和实验组(通过755 nm顺序治疗)长脉冲变石激光器和595 nm染料激光器)。
结果:对照组总有效率36.1%,实验组有76.3%。通过X2-检验比较枚举数据。结果被认为在P <.05上具有统计学意义。
结论:采用755nm脉冲染料激光和595nm长脉冲变石激光进行序贯治疗是治疗较深或较厚血管瘤的一种安全有效的方法。

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