BACKGROUND:This study was performed to explore the total prostate-specific antigen (tPSA) concentration, free PSA (fPSA) concentration, free-to-total PSA ratio (% fPSA), tPSA density (tPSAD), and neutrophil-to-lymphocyte ratio (NLR) in blood in patients with concurrent benign prostatic hyperplasia (BPH) and histologic prostatitis, and to provide new ideas for the diagnosis of prostatitis. METHODS:Patients who underwent transurethral bipolar plasmakinetic prostatectomy from June 2017 to June 2018 were retrospectively divided into two groups according to the degree of pathological inflammation of the resected prostate tissue: group A (BPH with histologic acute and chronic inflammation), group B (BPH with histologic chronic inflammation). The preoperative PSA-related indexes and NLR in blood were respectively compared between two groups. RESULTS:Groups A and B comprised 59 and 41 cases, respectively. The values of tPSA, tPSAD, and NLR were all significantly higher in group A than B, and the value of % fPSA was significantly lower in group A than B (p < 0.05). There was no significant difference for the value of fPSA between the two groups (p > 0.05). CONCLUSIONS:Histologic acute prostatitis can cause changes of PSA-related indexes and NLR in blood, which has important clinical significance in diagnosis of prostatitis.

译文

背景:本研究旨在探讨总前列腺特异性抗原(tPSA)浓度,游离PSA(fPSA)浓度,游离总PSA比率(%fPSA),tPSA密度(tPSAD)和嗜中性白细胞至淋巴细胞并发良性前列腺增生(BPH)和组织学性前列腺炎患者血液中的血脂比(NLR),为前列腺炎的诊断提供新思路。
方法:根据切除的前列腺组织的病理炎症程度,将2017年6月至2018年6月行经尿道双极血浆动力学前列腺切除术的患者回顾性分为两组:A组(伴有组织性急,慢性炎症的BPH),B组(BPH)组织学慢性炎症)。比较两组患者术前PSA相关指标和血液中的NLR。
结果:A组和B组分别包括59例和41例。 A组的tPSA,tPSAD和NLR值均显着高于B,A组的%fPSA值显着低于B(p <0.05)。两组之间的fPSA值无显着差异(p> 0.05)。
结论:组织学急性前列腺炎可引起血液中PSA相关指标和NLR的改变,对前列腺炎的诊断具有重要的临床意义。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录