We report a case of "recall-like phenomenon" caused by nonionic contrast medium. A 62-year-old woman suffering from postherpetic neuralgia developed erythematous plaques 12 h after an intercostal nerve block under X-ray guidance using iohexol (Omnipaque) as contrast medium. The erythematous plaques were preferentially located in the sites where she had experienced herpes zoster 4 months previously. The lesions cleared spontaneously leaving no pigmentation. Both patch testing and intradermal testing with iohexol and ioversol were positive. We postulate that local immunological changes in the skin, such as an increased number and/or accelerated activity of Langerhans cells and mast cells in the herpes zoster lesions, were responsible for this phenomenon. This "recall-like phenomenon", occurring preferentially in skin previously affected by herpes zoster, could facilitate understanding of the pathology of drug eruptions.

译文

我们报告了一例由非离子造影剂引起的 “召回现象”。一名患有带状疱疹后神经痛的62岁妇女在x射线引导下使用碘海醇 (Omnipaque) 作为造影剂在肋间神经阻滞后12小时出现红斑。红斑斑块优先位于她4个月前经历过带状疱疹的部位。病变自发清除,没有色素沉着。碘海醇和ioversol的贴片测试和皮内测试均为阳性。我们假设皮肤的局部免疫学变化,例如带状疱疹病变中朗格汉斯细胞和肥大细胞的数量增加和/或活性加速,是造成这种现象的原因。这种 “类似召回的现象” 优先发生在先前受带状疱疹影响的皮肤中,可以促进对药疹病理的理解。

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