OBJECTIVE:To compare the status of infants with hypoplastic left heart syndrome (HLHS) or pulmonary atresia-hypoplastic right heart (PA-HRH) before and following transport using the validated Transport Risk Index of Physiologic Stability (TRIPS) score.
METHODS:In this retrospective review of infants with HLHS or PA-HRH transported to a Children's Hospital by a pediatric transport team, an increase in TRIPS score (temperature, blood pressure, respiratory status, and response to stimuli) following transport was defined as deterioration. Statistical analyses included t-test (paired and independent), χ2, and McNemar's tests for comparisons between groups with and without deterioration and before and after transport.
RESULTS:Our cohort [n = 64; 39 (61%) HLHS and 25 (39%) PA-HRH] was predominantly female (61%), black (56%), and diagnosed antenatally (78%). Median transport time was 20 (10-30) min and age was <12 h in 48 (75%) infants. TRIPS scores worsened after transport in 24 (37.5%) infants, due to temperature (n = 10) or respiratory (n = 7) dysregulation. Infants who deteriorated during transport had HLH more often (83 versus 48%) and lower pH [7.27 (0.12) versus 7.33 (0.07)]. HLH was significantly predictive of deterioration during transport [OR 5.60 (95% C.I. 1.18-26.62)].
CONCLUSIONS:The physiologic deterioration in a third of infants with single ventricle following short transports is intriguing and may have implications on their optimal place of birth.
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【The effect of transport on the physiologic stability of neonates with ductal-dependent single-ventricle lesions.].
【运输对导管依赖性单心室病变新生儿的生理稳定性的影响。】
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DOI：10.1080/14767058.2017.1289164文章类型：杂志文章
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目的：使用经过验证的生理稳定性运输风险指数（TRIPS）评分，比较出生前后发育不良的左心综合征（HLHS）或肺动脉闭锁-发育不良的右心（PA-HRH）婴儿的状况。
方法：在本次回顾性回顾中，由儿科运输小组将HLHS或PA-HRH婴儿运输到儿童医院，将运输后TRIPS评分（温度，血压，呼吸状况和对刺激的反应）的升高定义为恶化。统计分析包括t检验（配对和独立），χ2和McNemar检验，用于比较运输前后有无恶化的组和没有恶化的组。
结果：我们的队列[n = 64; 39例（61％）HLHS和25例（39％）PA-HRH]以女性（61％），黑人（56％）和产前诊断（78％）为主。 48名（75％）婴儿的中位转运时间为20（10-30）min，年龄<12 h。由于温度（n = 10）或呼吸道（n = 7）失调，在24名（37.5％）的婴儿中运输后，TRIPS评分恶化。在运输过程中恶化的婴儿患HLH的频率更高（83％对48％）和较低的pH值[7.27（0.12）对7.33（0.07）]。 HLH显着预测了运输过程中的恶化[OR 5.60（95％C.I. 1.18-26.62）]。
结论：短途运输后三分之一单脑室婴儿的生理恶化是令人着迷的，并且可能对他们的最佳出生地点有影响。
方法：在本次回顾性回顾中，由儿科运输小组将HLHS或PA-HRH婴儿运输到儿童医院，将运输后TRIPS评分（温度，血压，呼吸状况和对刺激的反应）的升高定义为恶化。统计分析包括t检验（配对和独立），χ2和McNemar检验，用于比较运输前后有无恶化的组和没有恶化的组。
结果：我们的队列[n = 64; 39例（61％）HLHS和25例（39％）PA-HRH]以女性（61％），黑人（56％）和产前诊断（78％）为主。 48名（75％）婴儿的中位转运时间为20（10-30）min，年龄<12 h。由于温度（n = 10）或呼吸道（n = 7）失调，在24名（37.5％）的婴儿中运输后，TRIPS评分恶化。在运输过程中恶化的婴儿患HLH的频率更高（83％对48％）和较低的pH值[7.27（0.12）对7.33（0.07）]。 HLH显着预测了运输过程中的恶化[OR 5.60（95％C.I. 1.18-26.62）]。
结论：短途运输后三分之一单脑室婴儿的生理恶化是令人着迷的，并且可能对他们的最佳出生地点有影响。
