OBJECTIVE:To compare the status of infants with hypoplastic left heart syndrome (HLHS) or pulmonary atresia-hypoplastic right heart (PA-HRH) before and following transport using the validated Transport Risk Index of Physiologic Stability (TRIPS) score. METHODS:In this retrospective review of infants with HLHS or PA-HRH transported to a Children's Hospital by a pediatric transport team, an increase in TRIPS score (temperature, blood pressure, respiratory status, and response to stimuli) following transport was defined as deterioration. Statistical analyses included t-test (paired and independent), χ2, and McNemar's tests for comparisons between groups with and without deterioration and before and after transport. RESULTS:Our cohort [n = 64; 39 (61%) HLHS and 25 (39%) PA-HRH] was predominantly female (61%), black (56%), and diagnosed antenatally (78%). Median transport time was 20 (10-30) min and age was <12 h in 48 (75%) infants. TRIPS scores worsened after transport in 24 (37.5%) infants, due to temperature (n = 10) or respiratory (n = 7) dysregulation. Infants who deteriorated during transport had HLH more often (83 versus 48%) and lower pH [7.27 (0.12) versus 7.33 (0.07)]. HLH was significantly predictive of deterioration during transport [OR 5.60 (95% C.I. 1.18-26.62)]. CONCLUSIONS:The physiologic deterioration in a third of infants with single ventricle following short transports is intriguing and may have implications on their optimal place of birth.

译文

目的:使用经过验证的生理稳定性运输风险指数(TRIPS)评分,比较出生前后发育不良的左心综合征(HLHS)或肺动脉闭锁-发育不良的右心(PA-HRH)婴儿的状况。
方法:在本次回顾性回顾中,由儿科运输小组将HLHS或PA-HRH婴儿运输到儿童医院,将运输后TRIPS评分(温度,血压,呼吸状况和对刺激的反应)的升高定义为恶化。统计分析包括t检验(配对和独立),χ2和McNemar检验,用于比较运输前后有无恶化的组和没有恶化的组。
结果:我们的队列[n = 64; 39例(61%)HLHS和25例(39%)PA-HRH]以女性(61%),黑人(56%)和产前诊断(78%)为主。 48名(75%)婴儿的中位转运时间为20(10-30)min,年龄<12 h。由于温度(n = 10)或呼吸道(n = 7)失调,在24名(37.5%)的婴儿中运输后,TRIPS评分恶化。在运输过程中恶化的婴儿患HLH的频率更高(83%对48%)和较低的pH值[7.27(0.12)对7.33(0.07)]。 HLH显着预测了运输过程中的恶化[OR 5.60(95%C.I. 1.18-26.62)]。
结论:短途运输后三分之一单脑室婴儿的生理恶化是令人着迷的,并且可能对他们的最佳出生地点有影响。

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