BACKGROUND & AIMS:
:The purpose of this study was to compare fatigue, strength, body composition, muscle thickness, and muscle quality between Hodgkin's lymphoma survivors (HLS) and apparently healthy subjects matched by age, gender, and physical activity levels (CON). Twelve HLS (32.16 ± 8.06) and 36 CON (32.42 ± 7.64) were enrolled in the study. Fatigue was assessed using the 20-item Multidimensional Fatigue Inventory, muscle strength using an isokinetic dynamometer, body composition using dual-energy X-ray absorptiometry, and thickness and muscle quality using B-mode ultrasound. Differences between HLS and CON were analyzed using independent samples t tests. No significant differences were observed between groups for any demographic characteristics: age ( P = .922), weight ( P = .943), height ( P = .511), body mass index ( P = .796), fat mass ( P = .688), fat-free mass ( P = .520), and percent body fat ( P = .446). No significant differences were observed for strength (peak torque; P = .552), relative peak torque ( P = .200), muscle thickness ( P > .05) and muscle quality ( P > .05). However, self-perceived fatigue was significantly higher in HLS than in CON ( P = .009). It appears that when HLS are matched by age and physical activity levels to CON, no significant difference in body composition, muscle thickness, muscle quality, or strength is observed. Self-perceived fatigue, as predicted, is higher in HLS, which may have implications and should be considered when prescribing exercise training to this cancer population.
背景与目标:
: 这项研究的目的是比较霍奇金淋巴瘤幸存者 (HLS) 与年龄,性别和身体活动水平 (CON) 匹配的明显健康受试者之间乏力,力量,身体成分,肌肉厚度和肌肉质量。12个HLS (32.16 ± 8.06) 和36个CON (32.42 ± 7.64) 被纳入研究。乏力20个项目的多维乏力清单,使用等速测力计评估肌肉力量,使用双能x射线吸收仪评估身体成分,以及使用b型超声评估厚度和肌肉质量。使用独立样本t检验分析了HLS和CON之间的差异。年龄 (P = .922),体重 (P = .943),身高 (P = .511),体重指数 (P = .796),脂肪量 (P = .688),无脂肪量 (P = .520),和体脂百分比 (P = .446)。强度 (峰值扭矩; P = .552),相对峰值扭矩 (P = .200),肌肉厚度 (P> .05) 和肌肉质量 (P> .05) 均无显着差异。然而,HLS的自我感知乏力明显高于CON (P = .009)。看来,当HLS按年龄和身体活动水平与CON相匹配时,未观察到身体成分,肌肉厚度,肌肉质量或力量的显着差异。正如预测的那样,HLS的自我感知乏力较高,这可能会产生影响,在对该癌症人群进行运动训练时应予以考虑。