Sixteen patients with increased intraocular pressure (over 20 mm Hg) received 25 and 50 mg of oral methazolamide, twice daily, during consecutive weeks and then 500 mg (Sequels) of acetazolamide. The two methazolamide regimens produced significant decreases in intraocular pressure. Acetazolamide treatment resulted in a greater decrease in intraocular pressure but more systemic acidosis and side effects.

译文

16名眼内压升高 (超过20毫米Hg) 的患者在连续几周内每天两次接受25和50 mg口服美沙唑胺,然后接受500 mg (续集) 乙酰唑胺。两种甲唑胺方案可显着降低眼内压。乙酰唑胺治疗导致眼内压下降幅度更大,但全身酸中毒和副作用更大。

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