BACKGROUND:Systemic acetazolamide treatment has been reported in association with Stevens-Johnson syndrome (SJS). This is the first report of this syndrome associated with methazolamide treatment. The association is reported in two Japanese-American women.
METHOD AND RESULTS:Two patients with SJS, which developed during treatment with methazolamide, are described. Other potential associations are discussed.
CONCLUSIONS:Systemically administered carbonic anhydrase inhibitors, including both acetazolamide and methazolamide can be associated with SJS.
METHOD AND RESULTS:Two patients with SJS, which developed during treatment with methazolamide, are described. Other potential associations are discussed.
CONCLUSIONS:Systemically administered carbonic anhydrase inhibitors, including both acetazolamide and methazolamide can be associated with SJS.