A randomised trial was undertaken to compare the effect of three oral care protocols in delaying the onset of stomatitis and reducing oral injury in nasopharyngeal cancer patients undergoing radiotherapy, 30 eligible patients with a mean age of 56.2 years were recruited and evenly allocated to one of the three groups using a randomly permuted blocks method. Patients allocated to group E1 and group E2 were given the same instructions on oral care at 1 day, and 1 week before radiotherapy, respectively, while those allocated to the control group were given no instructions. We use the Oral Assessment Guide to assess the oral physical conditions of these patients daily. Our findings revealed that the patients in the E2 group not only had later onset of stomatitis than those in the control and the E1 groups, but also had lesser degree of oral injury measured by the overall assessment score. We thereby recommend the use of the E2 protocol for delaying the onset of stomatitis and reducing oral injury in nasopharyngeal cancer patients undergoing radiotherapy.

译文

进行了一项随机试验,以比较三种口腔护理方案在延迟接受放射治疗的鼻咽癌患者的口腔炎发作和减少口腔损伤方面的效果。招募了30名平均年龄为56.2岁的合格患者,并使用随机置换块方法将其平均分配给三组之一。分配给E1组和E2组的患者分别在放疗前1天和1周接受相同的口腔护理指导,而分配给对照组的患者则没有给予指导。我们使用《口腔评估指南》每天评估这些患者的口腔身体状况。我们的发现表明,E2组的患者不仅比对照组和E1组的患者口腔炎发作晚,而且通过总体评估评分测量的口腔损伤程度也较小。因此,我们建议使用E2方案来延迟接受放射治疗的鼻咽癌患者的口腔炎发作并减少口腔损伤。

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