From 1982 to 1987, 2,433 lesions of the thyroid gland in 1,796 patients were examined by fine needle aspiration (FNA). Cytopathology classified 66.91% of the aspirates as benign, 10.76% as thyroiditis, 4.89% as suspected (unspecified) neoplasia, 1.31% as positive for malignancy and 16.11% (392) as unsatisfactory. The histologic diagnoses in 257 cases were compared with cytologic diagnoses to determine the accuracy of FNA cytology of thyroid lesions, yielding a sensitivity of 71.43%, a specificity of 100% and an accuracy of 95.09%. This data strongly supports thyroid FNA as an important preoperative diagnostic tool. Follicular carcinomas were difficult to cytologically differentiate from nonmalignant follicular neoplasms, and papillary thyroid carcinomas less than 2 cm in diameter in elderly patients were frequently misdiagnosed or diagnosed only as "suspect lesion."

译文

:从1982年到1987年,通过细针穿刺术(FNA)检查了1,796例患者的2,433例甲状腺的病变。细胞病理学将良性抽吸物分为66.91%,甲状腺炎为10.76%,疑似肿瘤(未指明)为4.89%,恶性肿瘤阳性为1.31%,不满意为16.11%(392)。将257例患者的组织学诊断结果与细胞学诊断结果进行比较,以确定FNA甲状腺病变细胞学检查的准确性,其敏感性为71.43%,特异性为100%,准确性为95.09%。该数据强烈支持甲状腺FNA作为重要的术前诊断工具。滤泡状癌很难在细胞学上与非恶性滤泡性肿瘤区分开,并且老年患者中直径小于2 cm的乳头状甲状腺癌经常被误诊或仅诊断为“可疑病变”。

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