UNLABELLED:In the first population-based study of vertebral fractures in Latin America, we found a 11.18 (95% CI 9.23-13.4) prevalence of radiographically ascertained vertebral fractures in a random sample of 1,922 women from cities within five different countries. These figures are similar to findings from studies in Beijing, China, some regions of Europe, and slightly lower than those found in the USA using the same standardized methodology. INTRODUCTION:We report the first study of radiographic vertebral fractures in Latin America. METHODS:An age-stratified random sample of 1,922 women aged 50 years and older from Argentina, Brazil, Colombia, Mexico, and Puerto Rico were included. In all cases a standardized questionnaire and lateral X-rays of the lumbar and thoracic spine were obtained after informed consent. RESULTS:A standardized prevalence of 11.18 (95% CI 9.23-13.4) was found. The prevalence was similar in all five countries, increasing from 6.9% (95% CI 4.6-9.1) in women aged 50-59 years to 27.8% (95% CI 23.1-32.4) in those 80 years and older (p for trend < 0.001). Among different risk factors, self-reported height loss OR = 1.63 (95% CI: 1.18-2.25), and previous history of fracture OR = 1.52 (95% CI: 1.14-2.03) were significantly (p < 0.003 and p < 0.04 respectably) associated with the presence of radiographic vertebral fractures in the multivariate analysis. In the bivariate analyses HRT was associated with a 35% lower risk OR = 0.65 (95% CI: 0.46-0.93) and physical activity with a 27% lower risk of having a vertebral fracture OR = 0.73 (95% CI: 0.55-0.98), but were not statistically significant in multivariate analyses CONCLUSION:We conclude that radiographically ascertained vertebral fractures are common in Latin America. Health authorities in the region should be aware and consider implementing measures to prevent vertebral fractures.

译文

在拉丁美洲进行的第一项基于人群的脊椎骨折研究中,我们从五个国家/地区的1,922名妇女中随机抽取了X线照片确定的脊椎骨折患病率,分别为11.18(95%CI 9.23-13.4)。这些数字与在中国北京,欧洲某些地区的研究结果相似,但略低于在美国使用相同标准化方法得出的结果。
简介:我们报告了拉丁美洲的首例放射学性脊椎骨折研究。
方法:采用年龄分层的随机抽样方法,对来自阿根廷,巴西,哥伦比亚,墨西哥和波多黎各的1,922名年龄在50岁以上的女性进行了抽样。在所有情况下,经过知情同意后,可获得一份标准化的问卷以及腰椎和胸椎的X线片。
结果:标准化患病率为11.18(95%CI 9.23-13.4)。这五个国家的患病率相似,从50-59岁女性的6.9%(95%CI 4.6-9.1)上升到80岁以上女性的27.8%(95%CI 23.1-32.4)(趋势

结论:我们得出结论,放射照相确定的椎体骨折在拉丁美洲很常见。该地区的卫生部门应了解并考虑采取预防椎骨骨折的措施。

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