The lifetime incidence of mood disorders is twice as great in women compared with men, with the highest risk occurring during the childbearing years. The management of mental illness during pregnancy and lactation is a particularly complex clinical situation. The cornerstone of such a clinical decision is a completion of an assessment of the risks of the illness vs the risks of treatment. The following article reviews the factors influencing infant outcome and outlines the essential elements of the process of determining risk for the use of psychotropics in women during pregnancy and lactation. As the available data rapidly change, the facets of the risk benefit assessment are consistent and often the issue of specific medication is decided by prior history and exposure.

译文

:一生中,情绪障碍的发生率是女性的两倍,是男性,在育龄期间发生的风险最高。妊娠和哺乳期精神疾病的治疗是一种特别复杂的临床情况。这种临床决策的基础是完成对疾病风险与治疗风险的评估。以下文章回顾了影响婴儿结局的因素,并概述了确定孕妇在怀孕和哺乳期间使用精神药物的风险的过程的基本要素。随着可用数据的快速变化,风险收益评估的各个方面是一致的,并且特定药物的问题通常取决于先前的病史和接触情况。

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