OBJECTIVE:To evaluate the clinical characteristics and laboratory test results in pregnant women with coronavirus disease 2019 (COVID-19). METHODS:A retrospective study to review and compare clinical data including electronic medical records and laboratory tests from pregnant and nonpregnant patients admitted the Central Hospital of Wuhan, China from December 8, 2019 to April 1, 2020. RESULTS:A total of 72 women (30 pregnant and 42 nonpregnant) with COVID-19 were included. No patients developed severe pneumonia during the study. Compared with the nonpregnant group, pregnant patients were admitted to hospital earlier (0.25 vs 11.00 days; P<0.001), presented milder symptoms, had a higher rate of asymptomatic infection (26.7% vs 0%), and shorter length of hospital stay (14.5 vs 17.0 days; P<0.01). Laboratory test results showed that levels of inflammation markers such as white blood cell count, neutrophil count and percentage, C-reactive protein, procalcitonin, and D-dimer were significantly higher in pregnant women, whereas mean lymphocyte percentage was significantly lower compared with nonpregnant women. CONCLUSION:In some respects, the clinical characteristics and laboratory test results of COVID-19 in pregnant patients seems to be distinctive from their nonpregnant counterparts. Appropriate advice and positive treatment might be critical to the prognosis when dealing with these pregnant patients. Pregnant patients with COVID-19 had their own positive clinical characteristics and special laboratory test results. Responsive medical advice and active treatment for those patients are critical to recovery.

译文

目的:评估2019年冠状病毒病孕妇的临床特征和实验室检查结果(COVID-19)。
方法:一项回顾性研究,旨在回顾和比较2019年12月8日至2020年4月1日收治于中国武汉市中心医院的孕妇和非孕妇的临床数据,包括电子病历和实验室检查结果。
结果:总共包括72例COVID-19的妇女(30例孕妇和42例未妊娠)。在研究期间,没有患者出现严重的肺炎。与未怀孕组相比,怀孕患者较早入院(0.25 vs 11.00天; P <0.001),症状较轻,无症状感染率较高(26.7%vs 0%),住院时间较短( 14.5天与17.0天; P <0.01)。实验室测试结果显示,孕妇的炎症标志物(如白细胞计数,中性粒细胞计数和百分比,C反应蛋白,降钙素和D-二聚体)的水平显着较高,而平均淋巴细胞百分比与未怀孕的女性相比明显较低。 。
结论:在某些方面,COVID-19在孕妇中的临床特征和实验室检查结果似乎与非孕妇有区别。当与这些怀孕的患者打交道时,适当的建议和积极的治疗可能对预后至关重要。孕妇的COVID-19患者具有自己的阳性临床特征和特殊的实验室检查结果。对这些患者的响应性医疗建议和积极治疗对于康复至关重要。

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