The recognition that human papillomavirus (HPV) infection is the central, necessary cause of cervical cancer paved the way to new fronts of prevention via improved screening methods and HPV vaccination. Much has been learned in all fronts, from the molecular basis of our understanding of how HPV causes disease to the health economics of preventive strategies at the individual and population levels. Progress in other areas of cancer control has yet to show the same multi- and trans-disciplinary gains seen in research on HPV-associated malignancies, which is one of the unequivocal success stories in disease prevention. Yet, as an embarrassment of riches, much more research is needed to fill the gaps in knowledge that remain before we are able to reap the benefits from the knowledge translation from all fronts. Public health research on setting-specific implementation of HPV-based preventive strategies and more concerted advocacy to counter barriers facing the adoption of these strategies are likely to yield major dividends in reducing the burden of HPV-associated diseases. This article forms part of a special supplement entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012.

译文

:认识到人乳头瘤病毒(HPV)感染是子宫颈癌的主要,必要原因,这通过改进的筛查方法和HPV疫苗接种为预防的新领域铺平了道路。从我们对HPV引起疾病的理解的分子基础到个人和人群的预防策略的健康经济学,在各个方面都学到了很多。其他癌症控制领域的进展尚未显示出与HPV相关的恶性肿瘤研究相同的多学科和跨学科研究成果,这是疾病预防方面明确的成功案例之一。然而,作为财富的尴尬,我们需要进行更多的研究来填补知识上的空白,才能使我们从各个方面受益于知识翻译。关于针对特定人群实施基于HPV的预防策略的公共卫生研究,以及更一致地倡导应对采用这些策略所面临的障碍,可能会在减轻与HPV相关疾病的负担方面产生重大成果。本文是标题为“ HPV感染和相关疾病的综合控制”疫苗第30卷,补编5、2012年的特殊补编的一部分。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录