BACKGROUND:Although primary headache is the most frequent neurological disorder and there is some evidence that the prevalence rates have increased in recent years, no long-term data on the annual prevalence of headache are available for Germany. The objective of the study was therefore to obtain long-term data on the period prevalence of headache in the general population in Germany by means of population-based cross-sectional annual surveys (1995-2005 and 2009). METHODS:These surveys were conducted as face-to-face paper-and-pencil interviews from 1995 through 2004, and from 2005 onwards as computer-aided personal interviews. The reported headaches were self-diagnosed by the interviewees. Per year, approximately 640 trained interviewers interviewed between 10,898 and 12,538 German-speaking individuals aged 14 and older and living in private households in the whole of Germany (response rate: 67.4% and 73.1%, gross samples: 16,026 to 18,176 subjects). A total of more than 146,000 face-to-face interviews were analyzed. RESULTS:The one-year headache prevalence remained stable over the entry period, with 58.9% (95%CI 57.7-60.1) to 62.5% (95%CI 61.3-63.7) (p=0.07). Women showed consistently higher prevalence rates than men (females: 67.3 (95%CI 65.7-68.9) to 70.7% (95%CI 69.1-72.3), males: 48.4% (95%CI 46.5-50.3) to 54.3% (95%CI 52.4-56.2)), and both sexes showed a bell-shaped age dependence with peaks in the 30-39 age group. A stable slightly higher prevalence was observed in urban versus rural areas (p<0.0001), and there was also a significant trend towards higher prevalence rates in groups with a monthly household income larger than 3,500 € (p=0.03). CONCLUSION:The overall headache prevalence remained stable in Germany in the last 15 years.

译文

背景:尽管原发性头痛是最常见的神经系统疾病,并且有一些证据表明近年来的患病率有所增加,但是德国尚无关于每年头痛患病率的长期数据。因此,本研究的目的是通过基于人口的横断面年度调查(1995-2005年和2009年),获得有关德国普通人群头痛期间患病率的长期数据。
方法:这些调查从1995年至2004年以面对面的纸笔访谈方式进行,从2005年开始以计算机辅助的个人访谈方式进行。所报告的头痛是由受访者自我诊断的。每年,大约有640名受过训练的访调员采访了全德国10,898至12,538名14岁及以上,居住在私人家庭中的德语人士(答复率:67.4%和73.1%,总样本:16,026至18,176名受试者)。总共对超过146,000个面对面访谈进行了分析。
结果:一年期头痛患病率在入院期间保持稳定,从58.9%(95%CI 57.7-60.1)增至62.5%(95%CI 61.3-63.7)(p = 0.07)。女性的患病率一直高于男性(女性:67.3(95%CI 65.7-68.9)至70.7%(95%CI 69.1-72.3),男性:48.4%(95%CI 46.5-50.3)至54.3%(95% CI 52.4-56.2)),并且两性都显示出钟形的年龄依赖性,并且在30-39岁年龄组中达到峰值。观察到城市地区和农村地区的患病率略有稳定(p <0.0001),并且家庭月收入大于3500欧元的人群中患病率也有显着趋势(p = 0.03)。
结论:在过去的15年中,德国的总体头痛患病率保持稳定。

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