30 women (24-34 years; parity 3-6) randomly selected from the family planning clinic at Al-Azhar University Hospital, Cairo, were divided into 3 groups: 1) 10 normal fertile; 2) 10 women fitted with T-Cu-200 for 2-20 months; and 3) 10 women fitted with Lippes loop for 2-8 years. On the 13th-15th day of the cycle cervical mucus was sample and tested for sperm penetration, motility, turbidity, Spinnbarkeit, and ferning. Sperm penetration tests used the sperm migration meter of Kremer and turbidity and clarity were assessed by the naked eye. Sperm penetration and motility were greatly impaired with Cu-device users, while with Lippes loop the findings approached that of the normal control women. Turbidity results were significant (p less than .01) for Cu-device users. Diminished Spinnbarkeit and positive ferning were also observed in the presence of the Cu device. The impaired sperm penetration and immobilization with the use of the Cu-devices as opposed to Lippes loop suggests a local lethal effect of the increased copper on cervical mucus rather than a local foreign body reaction.

译文

从开罗Al-Azhar大学医院的计划生育诊所随机抽取30名妇女(24-34岁; 3-6岁),分为3组:1)10名正常可育; 2)正常生育。 2)10名装有T-Cu-200的妇女使用2-20个月; 3)10位装有Lippes环的女性,佩戴时间为2-8年。在周期的第13-15天对宫颈粘液进行取样并测试精子的渗透,运动性,浊度,Spinnbarkeit和精子。精子渗透测试使用Kremer精子迁移仪,用肉眼评估浊度和透明度。使用铜器的使用者会极大地损害精子的渗透和运动能力,而使用Lippes loop时,其结果接近于正常对照女性。铜装置用户的浊度结果显着(p小于0.01)。在铜装置的存在下,也观察到了纺锤形变小和正转角。与Lippes环相反,使用Cu装置导致精子穿透和固定受损,这表明增加的铜对子宫颈粘液的局部致死作用,而不是局部的异物反应。

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