We developed a novel multifaceted psychosocial intervention program which involves screening for psychological distress and comprehensive support including individually tailored psychotherapy and pharmacotherapy provided by mental health professionals. The purpose of the present study was to investigate the feasibility of the intervention program and its preliminary usefulness for reducing clinical psychological distress experienced by patients with recurrent breast cancer. The subjects who participated in the 3 months intervention program completed psychiatric diagnostic interview and several self-reported measures regarding psychological distress, traumatic stress, and quality of life. The assessments were conducted before the intervention (T1), after the intervention (T2), and 3 months after the intervention (T3). A total of 50 patients participated in the study. The rates of participation in and adherence to the intervention program were 85 and 86%, respectively. While the proportion of psychiatric disorders at T2 (11.6%) was not significantly different from that at T1 (22.0%) (p = 0.15), the proportion of that at T3 (7.7%) had significantly decreased compared with that at T1 (p = 0.005). The novel intervention program is feasible, is a promising strategy for reducing clinically manifested psychological distress and further controlled studies are warranted.

译文

:我们开发了一种新颖的多层面心理社会干预计划,涉及筛查心理困扰和综合支持,包括由心理健康专业人员提供的量身定制的心理治疗和药物治疗。本研究的目的是调查干预计划的可行性及其对减少复发性乳腺癌患者所经历的临床心理困扰的初步有用性。参加了为期3个月的干预计划的受试者完成了精神病学诊断性访谈,并就心理困扰,创伤压力和生活质量进行了几项自我报告的措施。评估是在干预之前(T1),干预之后(T2)和干预之后3个月(T3)进行的。共有50名患者参加了该研究。干预计划的参与率和遵守率分别为85%和86%。尽管T2的精神疾病比例(11.6%)与T1(22.0%)的比例无显着差异(p = 0.15),但T3的精神疾病的比例(7.7%)较T1(p = 0.005)。新的干预计划是可行的,是减少临床表现出的心理困扰的有前途的策略,因此有必要进行进一步的对照研究。

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