We describe a case of faecal microbiota transplantation (FMT) used for severe binary toxin-positive Clostridium difficile infection in an intensive care setting. The patient was admitted to the ICU of a tertiary hospital and failed traditional maximal pharmacological management. Adjunctive therapy with FMT given through gastroscopy resulted in resolution of the C. difficile-related symptoms. Although there is a growing experience with FMT for recurrent C. difficile infection, published evidence in severe disease is very limited. In a landscape of increasingly severe C. difficile infection, adjunctive FMT may be considered a useful early treatment option.

译文

:我们描述了在重症监护室中用于严重二重毒素阳性艰难梭菌感染的粪便微生物菌群移植(FMT)的情况。该患者入院于一家三级医院的ICU,传统的最大药物治疗失败。通过胃镜进行FMT的辅助治疗可解决艰难梭菌相关症状。尽管对于复发性艰难梭菌感染,FMT有越来越多的经验,但有关严重疾病的公开证据非常有限。在艰难梭菌感染日益严重的情况下,辅助性FMT可能被认为是一种有用的早期治疗选择。

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