A photoplethysmographic (PPG) technique to assess blood flow in bone tissue has been developed and tested. The signal detected by the PPG consists of a constant-level (DC) component-which is related to the relative vascularization of the tissue-and a pulsatile (AC) component-which is synchronous with the pumping action of the heart. The PPG probe was applied on the skin over the patella. The probe uses near-infrared (804 nm) and green (560 nm) light sources and the AC component of the PPG signals of the two wavelengths was used to monitor pulsatile blood flow in the patellar bone and the overlying skin, respectively. Twenty healthy subjects were studied and arterial occlusion resulted in elimination of PPG signals at both wavelengths, whereas occlusion of skin blood flow by local surface pressure eliminated only the PPG signal at 560 nm. In a parallel study on a physical model with a rigid tube we showed that the AC component of the PPG signal originates from pulsations of blood flow in a rigid structure and not necessarily from volume pulsations. We conclude that pulsatile blood flow in the patellar bone can be assessed with the present PPG technique.

译文

:已经开发并测试了用于评​​估骨组织中血流的光电容积描记(PPG)技术。 PPG检测到的信号由与组织的相对血管形成有关的恒定水平(DC)分量和与心脏的泵浦动作同步的脉动(AC)分量组成。将PPG探针施加到over骨上的皮肤上。该探头使用近红外(804 nm)和绿色(560 nm)光源,并且使用两种波长的PPG信号的AC分量分别监视monitor骨和周围皮肤中的脉动血流。对二十名健康受试者进行了研究,动脉阻塞导致两种波长的PPG信号均被消除,而局部表面压力阻塞皮肤血流仅消除了560 nm处的PPG信号。在具有刚性管的物理模型的并行研究中,我们显示了PPG信号的AC分量源自刚性结构中的血流脉动,而不一定源自体积脉动。我们得出的结论是,可以使用当前的PPG技术评估the骨中的搏动性血流。

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