Close and consistent adherence to anti-HIV medication regimens is necessary to achieve the maximum benefit of these potentially effective treatments. The authors examined cognitive and behavioral factors associated with HIV treatment adherence in a convenience sample of 112 women, 72 of whom were currently taking HIV treatments at the time of the study. Women completed confidential surveys and interviews to assess HIV-related health status, treatment regimens, and cognitive behavioral characteristics derived from the Information-Motivation-Behavioral Skills model of health promotion behaviors. Results showed that women who had missed at least one dose of their HIV medications in the past week reported lower intentions (motivation) to remain adherent and lower adherence self-efficacy (skills). Structural equation modeling showed that motivational and skills-building factors significantly predicted the number of medication doses missed. However, treatment-related information did not predict treatment adherence. In addition, women who had missed a dose of medication in the past week were more likely to have ever used devices and strategies to remind them of doses, but were no more likely to currently use such strategies. Interventions that enhance treatment adherence motivation and build adherence skills may help improve HIV treatment adherence in women receiving anti-HIV therapies.

译文

:为了获得这些潜在有效治疗的最大益处,必须密切一致地坚持抗HIV药物治疗方案。作者在便利的112名妇女样本中检查了与依从艾滋病治疗相关的认知和行为因素,其中有72名妇女在研究时目前正在接受艾滋病治疗。妇女完成了秘密调查和访谈,以评估从健康促进行为的信息动机-行为技能模型得出的艾滋病毒相关健康状况,治疗方案和认知行为特征。结果显示,在过去一周内错过了至少一剂HIV药物治疗的女性,其坚持依从的动机(动机)降低,依从自我效能(技能)降低。结构方程模型表明,动机因素和技能培养因素显着预测了错过的药物剂量数量。但是,与治疗有关的信息不能预测治疗的依从性。此外,在过去一周内未服药的女性更有可能曾经使用过设备和策略来提醒他们服药的剂量,但目前没有更多可能使用这种策略。增强治疗依从性动机并建立依从性技能的干预措施可能有助于提高接受抗HIV治疗的妇女对HIV治疗的依从性。

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