In this study the in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections was examined. Of 80 isolates (24 E. coli, 10 Enterobacter, 10 Klebsiella, 23 Proteus, 10 Pseudomonas, 2 Morganella and 1 Serratia) 49 were from inpatients, and 31 were from outpatients. Ciprofloxacin was the most potent compound and no resistant strain was found against ciprofloxacin, while 1 Enterobacter strain and 1 Pseudomonas strain were found to be resistant to both ofloxacin and pefloxacin. Another Pseudomonas strain was resistant to pefloxacin only. All of the resistant bacteria were from nosocomial infections.

译文

:在这项研究中,研究了氧氟沙星,培氟沙星和环丙沙星对从尿路感染中分离出来的各种革兰氏阴性细菌的体外活性。在80个分离株中(24个大肠杆菌,10个肠杆菌,10个克雷伯菌,23个变形杆菌,10个假单胞菌,2个摩根氏菌和1个沙雷氏菌)来自住院病人,而31个来自门诊病人。环丙沙星是最有效的化合物,未发现对环丙沙星具有抗药性的菌株,而发现1个肠杆菌菌株和1个假单胞菌菌株对氧氟沙星和培氟沙星均具有抗药性。另一假单胞菌菌株仅对培氟沙星具有抗性。所有耐药菌均来自医院感染。

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