The existence of depression among children or adolescents can trigger a sequence of burdens on themselves, their families and even the whole society, which cause both physical and economic impacts. Our network meta-analysis (NMA) was aimed at comparing them with each other for evaluating the optimal psychosocial therapy to help children and adolescents with depression to improve their mental health. Based on several biomedical databases, a system of search strategies was conducted for searching randomized controlled trials (RCTs) which published from their inception on October, 1st 2018 without language restriction. We carried out an expression analysis for comparing the efficacy of various psychosocial therapies using Bayesian NMA. A battery of analyses and assessments, such as conventional meta-analysis and risk of bias, were performed concurrently. Only 32 of RCTs which involved 2677 participants were eventually included in our analyses from the 19,176 of initial citation screening. In addition, in terms of various valid assessment instruments, interpersonal psychotherapy [standard mean difference (SMD) = -1.38, Credible interval (CrI) - 2.5, - 0.20)], computer cognitive-behavioral therapy (SMD = -1.36, CrI - 2.59, - 0.14), cognitive-behavioral therapy (SMD = -1.16, CrI - 2.15, - 0.18), had significantly better effects than the named control group. All together, these results suggest that interpersonal psychotherapy might be the best approach to improve the depressive state among children and adolescents. This study may provide an excellent resource for future endeavors to utilize psychosocial interventions and may also serve as a springboard for creative undertakings as yet unknown.

译文

:儿童或青少年抑郁症的存在会给自己,家庭乃至整个社会带来一系列负担,从而造成身体和经济上的双重影响。我们的网络荟萃分析(NMA)旨在将它们彼此进行比较,以评估最佳的心理治疗方法,以帮助患有抑郁症的儿童和青少年改善其心理健康。基于几个生物医学数据库,实施了一个搜索策略系统以搜索随机对照试验(RCT),该试验于2018年10月1日开始发布,没有语言限制。我们进行了表达分析,以比较使用贝叶斯NMA进行的各种心理社会疗法的疗效。同时进行了一系列分析和评估,例如常规的荟萃分析和偏倚风险。从19,176例首次引文筛选中,最终只有32篇RCT(涉及2677名参与者)被纳入我们的分析。此外,就各种有效的评估工具而言,人际心理治疗[标准平均差异(SMD)= -1.38,可信区间(CrI)-2.5,-0.20)],计算机认知行为疗法(SMD = -1.36,CrI- 2.59,-0.14),认知行为疗法(SMD = -1.16,CrI-2.15,-0.18)效果明显优于对照组。总之,这些结果表明,人际心理治疗可能是改善儿童和青少年抑郁状态的最佳方法。这项研究可以为将来利用社会心理干预的努力提供极好的资源,并且还可以作为尚不为人所知的创造性事业的跳板。

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