Since less than one-third of patients in need of a BMT find related donors, most patients will rely on registries of volunteer donors. For patients from minority ethnic groups the chances of finding matched unrelated donors are lower, in part due to the smaller representation of minorities in the registries. Our purpose was to determine the representation of Hispanics in the National Marrow Donor Program (NMDP), the largest registry of volunteer marrow donors in the United States. We analyzed a database provided by the NMDP that contained information on minorities. The number of Hispanic volunteer donors has increased 110-fold in the last 6 years. The proportion of Hispanics in the registry has also increased from 1.1% to 6%. Nevertheless, the proportion of Hispanic patients that received unrelated marrow transplants facilitated by the NMDP has increased only from 2.8% to 3.9% since 1989. Only 19.7% of the formal searches initiated by Hispanic patients resulted in transplants compared to the 30.4% observed in the Caucasian population. Despite increments in the number and proportion of Hispanic volunteer donors, the proportion of Hispanics that receive BMT from unrelated donors remains low. We conclude that, in addition to increased recruitment efforts, other strategies will be necessary in order to find enough marrow donors to meet the needs of the Hispanic population.

译文

由于需要BMT的患者中不到三分之一找到相关的捐献者,因此大多数患者将依赖志愿捐献者的登记簿。对于少数族裔的患者,找到匹配的无关亲属的机会较低,这部分是由于登记处中少数族裔的代表较少。我们的目的是确定西班牙裔美国人在国家骨髓捐献者计划(NMDP)中的代表情况,该计划是美国最大的志愿者骨髓捐献者注册表。我们分析了NMDP提供的数据库,其中包含有关少数群体的信息。在过去的6年中,西班牙裔志愿捐助者的数量增加了110倍。西班牙裔美国人在注册表中的比例也从1.1%增加到6%。然而,自1989年以来,接受NMDP促进的无关骨髓移植的西班牙裔患者比例仅从2.8%增至3.9%。由西班牙裔患者发起的正式搜索中只有19.7%进行了移植,而在美国,这一比例为30.4%。高加索人口。尽管拉美裔志愿捐助者的数量和比例有所增加,但从无关亲属捐助者那里接受BMT的拉美裔比例仍然很低。我们得出的结论是,除了加大招募力度之外,还需要其他策略,以便找到足够的骨髓捐献者来满足西班牙裔人口的需求。

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