OBJECTIVE:To investigate: (1) the course of coronary heart disease risk factors (lipid profiles and body mass index (BMI)) in the first five years after discharge from inpatient spinal cord injury (SCI) rehabilitation and (2) the association between lifestyle (physical activity, self-care related to fitness, smoking, alcohol, body mass and low-fat diet) and coronary heart disease risk factors during that period. DESIGN:Prospective cohort study. PARTICIPANTS/METHODS:Individuals with SCI (N=130). Total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides (TG) and BMI were determined at discharge from inpatient rehabilitation and 1 and 5 years after discharge. Using multilevel regression models, the effects of lifestyle (drinking alcohol, smoking, active lifestyle and self-care) on the lipid profiles and BMI were determined. RESULTS:After correction for lesion and personal characteristics, no changes in lipid profiles in the five years after discharge were seen, whereas the BMI increased significantly with 1.8 kg m(-2). A high percentage was at risk of cardiovascular disease due to high BMI (63-75%) or HDL (66-95%). The individuals who indicated to maintain their fitness level as good as possible and the individuals with a low BMI showed better lipid profiles. Individuals with a more active lifestyle showed higher HDL levels. Individuals who avoid smoking showed a 1.5 kg m(-2) higher BMI. CONCLUSION:Lipid profiles seem to stabilize in the years after discharge from inpatient SCI rehabilitation, whereas the BMI increased. Lifestyle factors associated with a favorable lipid profile and BMI could be identified.

译文

目的:调查:(1)住院脊髓损伤(SCI)康复出院后的最初五年中,冠心病危险因素(血脂和体重指数(BMI))的病程,以及(2)在此期间的生活方式(体育锻炼,与健身,吸烟,饮酒,体重和低脂饮食有关的自我保健)和冠心病的危险因素。
设计:前瞻性队列研究。
参与者/方法:具有SCI的个人(N = 130)。在住院康复出院时以及出院后1和5年测定总胆固醇(TC),高密度脂蛋白(HDL),低密度脂蛋白(LDL),甘油三酸酯(TG)和BMI。使用多级回归模型,确定了生活方式(饮酒,吸烟,积极的生活方式和自我保健)对血脂和BMI的影响。
结果:校正病灶和个人特征后,出院后五年内血脂没有变化,而BMI显着增加,为1.8 kg m(-2)。高百分比的BMI(63-75%)或HDL(66-95%)导致罹患心血管疾病的风险较高。表示要尽可能保持健康水平的个体和BMI较低的个体表现出更好的血脂状况。生活方式更加活跃的人表现出较高的HDL水平。避免吸烟的人的BMI升高1.5 kg m(-2)。
结论:住院SCI康复出院后的几年中,脂质分布似乎稳定,而BMI升高。可以确定与良好的脂质状况和BMI相关的生活方式因素。

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