In the last few decades, the importance of selenium in human health has been the subject of numerous studies. It is believed that the physiological effects of selenium occur mainly through the function of selenoproteins, which incorporate selenium in the form of one or more selenocysteine residues. Recent advances in understanding the complex regulation of selenoprotein synthesis and functional characterization of several members of the selenoprotein family have contributed to an improved comprehension of the role(s) of selenium in human health and the great diversity of physiological pathways influenced by this trace element.

译文

:在过去的几十年中,硒在人类健康中的重要性一直是众多研究的主题。相信硒的生理作用主要通过硒蛋白的功能而发生,硒蛋白以一种或多种硒代半胱氨酸残基的形式掺入硒。在了解硒蛋白合成的复杂调控和硒蛋白家族几个成员的功能表征方面的最新进展有助于人们更好地理解硒在人体健康中的作用以及受该微量元素影响的多种生理途径。

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