PURPOSE:Glycine-arginine-alpha-ketoisocaproic acid (GAKIC) is a relatively new supplement that athletes and fitness enthusiasts ingest to enhance performance during anaerobic exercise. Therefore, the purpose of this study was to investigate the potential ergogenic effects of GAKIC ingestion during multiple bouts of resistance exercise. METHOD:Seven resistance-trained men participated in a randomized, counterbalanced, double-blind study. Participants were randomly assigned to placebo or GAKIC (10.2 g) and performed 5 sets of 75% of 1-repetition maximum leg press to failure. Total load volume was calculated by multiplying the 75% of 1-repetition maximum mass lifted by the sum of repetitions to failure. One week later, participants ingested the other supplement (placebo or GAKIC) and the same exercise protocol was performed (i.e., crossover). Blood lactate, glucose, and heart rate were determined preexercise and immediately postexercise. RESULTS:GAKIC supplementation significantly increased leg-press total load volume (GAKIC = 31,564 +/- 9,132 kg; placebo = 25,763 +/- 6,595 kg, p < .05). Heart rate and blood lactate were significantly increased (p < .05) postexercise compared with preexercise but were not significantly different between GAKIC and placebo. No significant changes (p > .05) were detected for one-repetition maximum and blood glucose. CONCLUSIONS:These novel findings suggest that GAKIC increases total work performed during repeated bouts of lower-body resistance exercise. Thus, our data suggest that GAKIC ingestion before weight training may increase the training volume of athletes and resistance-trained individuals.

译文

用途:甘氨酸-精氨酸-α-酮异己酸(GAKIC)是运动员和健身爱好者摄取的相对较新的添加剂,可增强无氧运动时的表现。因此,本研究的目的是研究在多次抵抗运动中摄入GAKIC的潜在人体作用。
方法:七名经过抗性训练的男人参加了一项随机,平衡,双盲研究。将参与者随机分配到安慰剂或GAKIC(10.2克)中,并进行5组1次重复最大腿部按压至失败的75%。通过将举起的1次重复最大质量的75%乘以重复的失败次数之和来计算总负载量。一周后,参与者摄入了另一种补充剂(安慰剂或GAKIC),并执行了相同的锻炼方案(即交叉)。在运动前和运动后立即测定血乳酸,葡萄糖和心率。
结果:GAKIC补充剂显着增加了腿部按压的总负荷量(GAKIC = 31,564 /-9,132 kg;安慰剂= 25,763 /-6,595 kg,p <.05)。与运动前相比,运动后的心率和血液乳酸水平显着增加(p <.05),但GAKIC和安慰剂之间无显着差异。没有发现一次重复最大血糖和血糖的显着变化(p> .05)。
结论:这些新颖的发现表明,GAKIC增加了在反复进行下半身抵抗运动中的总工作量。因此,我们的数据表明,在进行负重训练之前摄入GAKIC可能会增加运动员和接受阻力训练的个人的训练量。

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