1. The specific radioactivity of [(14)C]glycerol released during the incubation of brown fat with [(14)C]glucose is much greater than that of the tissue lipid glycerol. 2. From a study of the release of [(14)C]glycerol from pre-labelled brown fat, it is concluded that the tissue contains a pool of glycerides with a higher rate of turnover than those in the main lipid store. 3. This pool contains newly synthesized glycerides, has a half-life of 25-30min and supplies about 25% of the glycerol liberated by brown fat. 4. Thus, a significant fraction of the total (14)C incorporated from glucose into brown-fat lipids is released as [(14)C]glycerol during an incubation.

译文

:1。在褐色脂肪与[(14)C]葡萄糖孵育期间释放的[(14)C]甘油的比放射性比组织脂质甘油的比放射性大得多。 2.根据对预先标记的棕色脂肪中[[14] C]甘油释放的研究,得出的结论是,组织中的甘油酯库比主要脂质库中的甘油酯转化率更高。 3.该池包含新合成的甘油酯,半衰期为25-30分钟,并提供约25%的棕色脂肪释放的甘油。 4.因此,在孵育过程中,从葡萄糖掺入褐脂脂质的总(14)C中有很大一部分作为[(14)C]甘油释放。

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